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Zilico Limited

How Does ZedScan Work?

  • ZedScan uses Electrical Impedance Spectroscopy (EIS) to differentiate between normal, pre-cancerous and cancerous tissue on the cervix according to its electrical properties
  • These properties are known to change during the development of neoplasia, with more dysplastic tissue exhibiting a reduced resistance to the flow of current as a result of physical changes in its structure
  • ZedScan measures the electrical impedance at 14 different frequencies which creates a characteristic spectrum according to the structure of the tissue (see Fig. 1)
  • Each reading is given a nominal value which is compared to a reference, providing a semi-quantitative, reproducible  assessment of the cervix
     

      Fig.1: Diagram showing different EIS spectra for cervical tissueElectrical Impedance Spectra of cervical epithelial tissue